Beth Israel Deaconess Medical Center Research Fellows in Boston, Massachusetts

Research Fellows

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Job LocationBoston, Massachusetts

Req ID 17397BR

Department Description: Description: We are seeking highly qualified applicants for a postdoctoral position to study oncogenic signaling pathways in primary brain cancer using state-of-the-art genetically engineered mouse models of brain cancer and global phosphoproteomics technology. The primary focus for this position is to dissect molecular mechanisms of sensitivity and resistance to therapeutic interventions. The multidisciplinary nature of this research project will allow the postdoctoral fellow to utilize a wide range of sophisticated techniques including cellular and molecular biology, microscopy, in vitro cell culture, in vivo animal models and MS-based proteomics. This position is available immediately.

Requirements: The ideal candidate should have been awarded or has completed the requirements for a doctoral (Ph.D.) degree in cellular and molecular biology, genetics or cancer biology. Applicants must have demonstrated research experience in several of the following techniques: i) in vitro cell culture and cell-based assays, ii) molecular biology techniques such as DNA isolation and RT-PCR, protein isolation/purification and western blotting, gel electrophoresis, flow cytometry, and confocal microscopy, iii)

use of tumor animal models. The candidate also has to have basic skills in computational biology/bioinformatics. The candidate must be able to work as part of a team, plan and perform experiments, analyze data, and communicate results in reports and scientific publications. Excellent verbal and written

communication skills, ability to manage research projects, and quickly learning new techniques are also essential.

The Genetics Division of BIDMC/HMS Department of Medicine: The Charest lab at BIDMC/HMS studies basic mechanisms of cancer with a focus on genetically relevant pre-/co-clinical primary brain cancer mouse

models. We utilize global proteomics and genomics approach for target discovery and cutting-edge in vivo gene modification techniques and pharmacological dissection of signaling pathway for validation of potential

clinical applications. The overarching goals of the lab are target discovery with immediate and impactful translation for patients in the clinic.Job Location: Boston, MAReq ID: 17397BRJob Summary: Has been awarded or has completed the requirements for a doctoral degree or foreign equivalent. Is a trainee pursuing advanced studies beyond the doctoral level in preparation for an independent career. In collaboration and under the mentorship of the Principle Investigator, a Research Fellow engages in activities that will further his or her professional development.

Essential Responsibilities:

  • Required Qualifications:

  • Doctoral degree required. Doctoral degree preferred.

  • 0-1 years related work experience required.

  • Advanced skills with Microsoft applications which may include Outlook, Word, Excel, PowerPoint or Access and other web-based applications. May produce complex documents, perform analysis and maintain databases.


  • Written Communications: Ability to summarize and communicate in English moderately complex information in varied written formats to internal and external customers.

  • Oral Communications: Ability to comprehend and communicate complex verbal information in English to medical center staff, patients, families and external customers.

  • Knowledge: Ability to demonstrate in-depth knowledge of concepts, practices and policies with the ability to use them in complex varied situations.

  • Team Work: Ability to lead collaborative teams for larger projects or groups both internal and external to the Medical Center and across functional areas. Results have implications for the management and operations of multiple areas of the organization.

  • Customer Service: Ability to provide a high level of customer service and staff training to meet customer service standards and expectations for the assigned unit(s). Resolves service issues in the assigned unit(s) in a timely and respectful manner.

Physical Nature of the Job:

Sedentary work: Exerting up to 10 pounds of force occasionally in carrying, lifting, pushing, pulling objects. Sitting most of the time, with walking and standing required only occasionally