Sanofi Group Principal Scientist in Framingham, Massachusetts

Principal Scientist


Sanofi Genzyme focuses on developing specialty treatments for debilitating diseases that are often difficult to diagnose and treat, providing hope to patients and their families.

Genzyme Corporation (a Sanofi company) and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

Job Responsibilities/Department Description:

The ideal candidate will join the BioProcess Analytics group and will work closely with the upstream and downstream BioProcess Development organization. Thecandidate is expected to take on a leading role managing a team and applying a diverse set of analytics/bioanalytical protein chemistry methods, as well as immunology-based assays to support Bioprocess development.


  • Lead a team of senior research associates and scientists responsible for high throughput and automated methods development for in-process analytical support testing.

  • Work with the team to develop new in-process analytical assays; improve existing methods; transfer current low throughput assays onto high throughput platforms.

  • Provide technical support and hands-on training for new assay development in LC-MS/MS analysis,HPLC/UPLC,CE-SDS and cIEF and immunology-based assays.

  • Develop ahigh level of employee engagement; mentor and train direct reports at varying levels of experience.Sets clear priorities for achieving results and empower the team to develop independent thinking skills.

  • Coordinate with management to plan workload and resources to meet project timelines and customers’ expectations.

  • Functions in a leadership role within Bioprocess Analytics; assistsin planning and project activities for Bioprocess Analytics.Manage priorities, and maintain timelines for multiple projects.

  • Contribute to documentation and preparation of reports and scientific presentations; participate indelivering scientific presentations at internal and external meetings.


Basic Qualifications:

  • PhD in Analytical Chemistry, Biochemistry or related field with 6 years relevant experience in Bioprocess Analytics environment.Previous management experience is required with aminimum of 3 years managing teams.

  • In-depth and broad knowledge in bio-analytical/analytical methods and immunology-based assay development platform technologies for protein characterization.Hands-on experience with mass spectrometry,HPLC/UPLC,CE-SDS and cIEF.Familiarity with qRT-PCR and biomolecular interaction assays, e.g. automated immunoassays, such as Octet and Gyros platforms

  • Proven track record as a leader with experience managing highly technical teams and buildinghigh performance teams.

Preferred Qualifications:

  • Experience in analytical methods development and qualification of therapeutic proteins, following ICH guidelinesfor the characterization

  • Knowledge of Process Analytical Technology (PAT) and development of at-line, on-line and in-line methods for process monitoring for downstream process monitoring is highly desirable.

  • Highly independent, driven, self-motivated and innovative thinker.Ability to work successfully in both a team/matrix environment as well as independently is essential

  • Excellent written, verbal communication and presentation skills

Job: Laboratory/Process/Device Development

Primary Location: United States-Massachusetts-Framingham

Job Posting: Sep 21, 2016, 11:31:47 AM

Job Type: Regular

Employee Status: Regular